Ana and Agnieszka Radwanska will meet for the tenth time on Sunday in the fourth round of Roland Garros. The Polish world No.4 holds a 6-3 head-to-head advantage.
Intriguingly, Ana won the opening three matches between the two, while Radwanska has won the last six. In fact, Ana has not won a set in the last five meetings.
The pair have faced one another twice already this year: Radwanska triumphed 6-2, 6-4 in the fourth round of the Australian Open and she won 6-1, 7-6 in the third round of Doha.
Ana advanced to the fourth round of the French Open with a 6-3, 6-2 victory over Frenchwoman Viriginie Razzano. The 14th seed triumphed in an hour and 13 minutes on court Philippe Chatrier.
Ana made a tentative start, double-faulting on the opening point and allowing her opponent to seize control of the rallies in game one: Razzano hammered her forehand.
The 25-year-old showed greater aggression in the following game and broke the world No.178.
Ana takes on world No.178 Virginie Razzano of France in the third round of the French open on Friday. It will be the sixth meeting between the pair, with Ana leading the head-to-head series 4-1.
Ana has won their last four matches: Razzano recorded a three-set win in Antwerp in 2005, when Ana was aged 17, but Ana is undefeated against the 29-year-old Frenchwoman ever since.
Most recently, Ana beat Razzano in Luxembourg in 2011.
Ana produced a dominant performance as she dismantled world No.94 Mathilde Johansson 6-2, 6-2 in the second round of the French Open. It was an overall pleasing display from the 25-year-old, who needed just 58 minutes to wrap up victory.
Ana takes on world No.94 Mathilde Johansson of France in the second round of the French Open on Wednesday. It will be the third meeting between the pair, with Ana leading the head-to-head series 2-0.
They last met in the opening round of the Madrid Open last year, when Ana triumphed 6-4, 6-1. Previously Johansson retired while trailing 6-2, 1-0 in an ITF Women's Circuit event in Batumi some nine years ago.
Johansson, who is two years older than Ana, reached round two with a surprise 7-5, 6-1 victory over world No.61 Chanelle Scheepers.
Overall, Ana was content with her performance during her 6-1, 3-6, 6-3 victory over Croatia's Petra Martic in the first round of the French Open on Sunday.
Ana overcame the first hurdle at the French Open as she beat Petra Martic of Croatia 6-1, 3-6, 6-3. The 2008 champion performed in a very accomplished style during sets one and three, but had to recover from a wobble in set two to reach the second round after 110 minutes of play.
Ana has been drawn to face Petra Martic of Croatia in the first round of the French Open, which begins in Paris on Sunday.
Should she overcome the world No.107, whom she has never before played, Ana will take on either Chanelle Scheepers or Mathilde Johansson in round two. 24th seed Julia Goerges is a potential third round opponent.
Fourth seed Agnieszka Radwanska of Poland could await in round four, while last year's conqueror Sara Errani (No.5) is a possible quarter-final opponent.
Images of Ana competing in last month's Porsche Tennis Grand Prix are now in the Galleries section.
As a result of her first round defeat at the Internazionali BNL d'Italia, Ana has slipped one place to No.14 in the latest WTA singles rankings, which are published today.
The rankings will be used to determine seedings at the French Open, which begins on Sunday, so Ana will be seeded 14th unless there is a withdrawal by a player (or players) ranked above her.
In the Race to the Championships Ana is also placed 14th.
Current WTA top 20:
